Issue: Số 1 - Tháng 1 - 2022Hóa học - Công nghệ thực phẩm
A study on the potential of Polyscias fruticosa (L.) Harms root extract to reduce blood glucose levels
Published: July 30, 2026
Abstract
Polyscias fruticosa (L.) Harms is known as a medicinal herb used in traditional medicine to prevent cough and reduce inflammatory. This study examines the potential of Polyscias fruticosa (L.) Harms root extract to reduce blood glucose levels in Swiss mice. The study’s experiments show that the aqueous extract of P. fruticosa caused no death in the mice (LD50 > 5000 mg/kg). The results of sub-acute toxicity tests shows that all the treated mice at the doses of 200 mg/kg survived throughout the 14 days of treatment. The test of blood glucose reducion potential shows that the root extract with the concentration of 200 mg/kg had no statistically significant difference compared with the glucose level of normal mice, and the weight of tested mice had no difference throughout treatment progress (p < 0.05). Staining of pancreatic tissue of mice by hematoxylin - eosin showed that the high ethanol can restore pancreatic islet cells.
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